RNA Details
Disease Name
primary myelofibrosis
Tissue
bone
RNA Symbol
mir-155
RNA ID
MI0000681
RNA Type
miRNA
Alteration Pattern
up regulation
Species
homo sapiens
Detection Methods
NA
Target
JARID2; NR4A3; CDC42; HMGB3
Pathway
NA
PubMed ID
25097177
Title
MiRNA-mRNA integrative analysis in primary myelofibrosis CD34+ cells: role of miR-155/JARID2 axis in abnormal megakaryopoiesis
Year
2014
Function
These findings suggest that overexpression of mir-155-5p and the resulting downregulation of jarid2 may contribute to mk hyperplasia in pmf.